SCHEMBL28061360

SCHEMBL28061360

CC(C)(C)C(N)c1ccc(O)c(-n2nc3ccc(Cl)cc3n2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.43
RAB9A P51151 5/20 0.43
LMNA P02545 3/20 0.43
KMT2A Q03164 6/20 0.40
MEN1 O00255 5/20 0.40
MAPT P10636 6/20 0.37
ALDH1A1 P00352 2/20 0.37
POLB P06746 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KDM4E B2RXH2 5/20 0.37
ATM Q13315 3/20 0.37
IDO1 P14902 1/20 0.33
PRKCZ Q05513 1/20 0.32
HSD17B10 Q99714 3/20 0.32
ALOX15 P16050 2/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
RECQL P46063 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7032725 0.85 NPC1 (0.46) NPC1RAB9ALMNAKMT2AMEN1
SCHEMBL11418479 0.82 NPC1 (0.51) NPC1RAB9ALMNAKMT2AMEN1
SCHEMBL29814292 0.80 NPC1 (0.46) NPC1RAB9ALMNAKMT2AMEN1
SCHEMBL351147 0.80 NPC1 (0.46) NPC1RAB9ALMNAKMT2AMEN1
SCHEMBL11622645 0.80 NPC1 (0.47) NPC1RAB9ALMNAKMT2AMEN1
SCHEMBL698631 0.78 NPC1 (0.69) NPC1RAB9ALMNAKMT2AMEN1
SCHEMBL30130370 0.78 NPC1 (0.69) NPC1RAB9ALMNAKMT2AMEN1
SCHEMBL6930071 0.78 MEN1 (0.58) NPC1RAB9ALMNAKMT2AMEN1
SCHEMBL1264030 0.78 CYP3A4 (0.50) NPC1RAB9ALMNAKMT2AMEN1
SCHEMBL30157198 0.78 CYP3A4 (0.50) NPC1RAB9ALMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109467630-B Ultrahigh molecular weight ethylene polymer powder and molded article using the same 旭化成株式会社 2019-11-12 CN disclosed
CN-109467630-A Ultrahigh molecular weight ethylene polymer powder and molded article using the same 旭化成株式会社 2019-03-15 CN disclosed
CN-103865145-B Polyethylene powder body, formed body and Separator for Lithium-ion battery 旭化成株式会社 2016-08-10 CN disclosed