Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14852910 | 0.86 | ALDH1A1 (0.35) | THRBLMNAMEN1NPC1RAB9A | |
| SCHEMBL15047334 | 0.84 | — | — | |
| SCHEMBL290098 | 0.79 | CDC7 (0.40) | LMNA | |
| SCHEMBL17589920 | 0.75 | LMNA (0.30) | LMNA | |
| SCHEMBL13047640 | 0.75 | ABL1 (0.30) | — | |
| SCHEMBL290931 | 0.75 | ABL1 (0.31) | — | |
| SCHEMBL13048000 | 0.73 | PAX8 (0.37) | ALDH1A1 | |
| SCHEMBL13074524 | 0.72 | HCAR2 (0.37) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL290377 | 0.69 | CYP11B2 (0.35) | — | |
| SCHEMBL13047439 | 0.69 | PIK3CG (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614826-B1 | Process for preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9357780-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2016-06-07 | — | — | US | disclosed |
| US-9357780-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2016-06-07 | — | — | US | disclosed |
| EP-2427191-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| EP-2427191-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| EP-2614825-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| EP-2604267-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2016-02-03 | — | — | EP | disclosed |
| EP-2604268-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2015-09-16 | — | — | EP | disclosed |
| US-9006446-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-9006446-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-20130089622-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-8350044-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-8350044-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2013-01-08 | — | — | US | disclosed |
| EP-2427191-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-18 | — | — | US | disclosed |
| WO-2010129497-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010129497-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | THRA 1310/4885THRB 518/4885PPARG 2473/4885 |
| US-20130089622-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | THRA 1310/4885THRB 518/4885PPARG 2473/4885 |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | THRA 1310/4885THRB 518/4885PPARG 2473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.