⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377180 | 0.81 | LDHA (0.57) | — | |
| SCHEMBL7931508 | 0.74 | — | — | |
| SCHEMBL12927368 | 0.74 | KDM4E (0.44) | — | |
| Glycine SCHEMBL3457792 | 0.74 | — | — | |
| SCHEMBL18432281 | 0.73 | — | — | |
| SCHEMBL122476 | 0.71 | — | — | |
| Glycine SCHEMBL8095196 | 0.70 | — | — | |
| Glycine SCHEMBL21879657 | 0.70 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL6239942 | 0.70 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL8585762 | 0.70 | GLRA1 (0.83) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9101662-B2 | Compositions with modulating agents | FOAMIX PHARMACEUTICALS LTD. (IL) | 2015-08-11 | — | — | US | claimed |
| US-8795693-B2 | Compositions with modulating agents | FOAMIX LTD. (IL) | 2014-08-05 | — | — | US | claimed |
| EP-2097065-A2 | FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS | Foamix Ltd. (IL) | 2009-09-09 | — | — | EP | claimed |
| WO-2008152444-A2 | FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS | FOAMIX LTD. (US) | 2008-12-18 | — | — | WO | claimed |
| US-20080206159-A1 | Drug mixture contains solvents, nonionic surfactants, gelling agent, therapeutic active agent, liquefied or compressed gas propellant; pressurized dispenser; treating skin diseases, dermal and mucosal delivery; stable and non-irritating emulsions | FOAMIX LTD. (IL) | 2008-08-28 | — | — | US | claimed |
| US-9101662-B2 | Compositions with modulating agents | FOAMIX PHARMACEUTICALS LTD. (IL) | 2015-08-11 | — | — | US | disclosed |
| US-8795693-B2 | Compositions with modulating agents | FOAMIX LTD. (IL) | 2014-08-05 | — | — | US | disclosed |
| US-20140080140-A1 | SCREENING FOR NEUROTOXIC AMINO ACID ASSOCIATED WITH NEUROLOGICAL DISORDERS | THE INSTITUTE FOR ETHNOMEDICINE | 2014-03-20 | — | — | US | disclosed |
| US-8541184-B2 | Screening for neurotoxic amino acid associated with neurological disorders | THE INSTITUTE FOR ETHNOMEDICINE (US) | 2013-09-24 | — | — | US | disclosed |
| US-8222276-B2 | Amine salt of carbostyril derivative | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-07-17 | — | — | US | disclosed |
| EP-2253619-B1 | Amine salt of carbostyril derivative | OTSUKA PHARMA CO LTD (JP) | 2012-03-14 | — | — | EP | disclosed |
| EP-1860441-B1 | Neurotoxic amino acid or neurotoxic derivative thereof associated with neurological disorders | INST ETHNOMEDICINE (US) | 2011-08-10 | — | — | EP | disclosed |
| EP-1664793-B1 | NEUROTOXIC AMINO ACID OR NEUROTOXIC DERIVATIVE THEREOF ASSOCIATED WITH NEUROLOGICAL DISORDERS | INST ETHNOMEDICINE (US) | 2007-11-07 | — | — | EP | disclosed |
| US-20070254315-A1 | SCREENING FOR NEUROTOXIC AMINO ACID ASSOCIATED WITH NEUROLOGICAL DISORDERS | THE INSTITUTE FOR ETHNOMEDICINE (US) | 2007-11-01 | — | — | US | disclosed |
| US-7256002-B2 | Screening for neurotoxic amino acid associated with neurological disorders | THE INSTITUTE FOR ETHNOMEDICINE (US) | 2007-08-14 | — | — | US | disclosed |
| US-20070155787-A1 | Amine salt of carbostyril derivative | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-07-05 | — | — | US | disclosed |
| CN-1860369-A | Neurotoxic amino acid or neurotoxic derivative thereof associated with neurological disorders | NAT TROPICAL BOTAN GARDEN (US) | 2006-11-08 | — | — | CN | disclosed |
| EP-1664793-A1 | NEUROTOXIC AMINO ACID OR NEUROTOXIC DERIVATIVE THEREOF ASSOCIATED WITH NEUROLOGICAL DISORDERS | Institute For Ethnomedicine (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005019830-A1 | NEUROTOXIC AMINO ACID OR NEUROTOXIC DERIVATIVE THEREOF ASSOCIATED WITH NEUROLOGICAL DISORDERS | INSTITUTE FOR ETHNOMEDICINE (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20050042686-A1 | Neurotoxic amino acid or neurotoxic derivative thereof associated with neurological disorders | NATIONAL TROPICAL BOTANICAL GARDEN | 2005-02-24 | — | — | US | disclosed |