Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | QDPR | P09417 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23411513 | 1.00 | TSHR (0.49) | TSHRSLC18A3SIGMAR1POLBHTR2C | |
| SCHEMBL14999422 | 0.94 | TSHR (0.54) | TSHRSLC18A3SIGMAR1POLBHTR2C | |
| Hydrochloric Acid SCHEMBL4891825 | 0.92 | TSHR (0.53) | TSHRSLC18A3SIGMAR1POLBHTR2C | |
| SCHEMBL14446350 | 0.85 | TSHR (0.54) | TSHRPOLB | |
| SCHEMBL29891550 | 0.82 | HTR2C (0.57) | SLC18A3SIGMAR1HTR2CHTR3A | |
| SCHEMBL16874642 | 0.82 | HTR2C (0.57) | SLC18A3SIGMAR1HTR2CHTR3A | |
| SCHEMBL29892026 | 0.79 | SLC18A3 (0.48) | SLC18A3SIGMAR1HTR2CHTR3AQDPR | |
| SCHEMBL23411134 | 0.79 | SLC18A3 (0.48) | SLC18A3SIGMAR1HTR2CHTR3AQDPR | |
| SCHEMBL22117611 | 0.78 | SLC18A3 (0.44) | TSHRSLC18A3SIGMAR1POLBHTR2C | |
| SCHEMBL17850376 | 0.76 | SLC18A3 (0.53) | SLC18A3SIGMAR1HTR2CHTR3AQDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119564686-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119523983-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119424429-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-115003665-B | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2024-11-08 | — | — | CN | disclosed |
| EP-4065574-A1 | SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION | Bayer Aktiengesellschaft (DE) | 2022-10-05 | — | — | EP | disclosed |
| CN-115003665-A | Substituted aminoquinolones as immunoactive DGK alpha inhibitors | 拜耳公司 | 2022-09-02 | — | — | CN | disclosed |