Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.81 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20553614 | 1.00 | SMN1; SMN2 (0.81) | SMN1; SMN2ACE2KMT2AL3MBTL1MAPT | |
| SCHEMBL21792720 | 0.99 | ACE2 (0.82) | SMN1; SMN2ACE2KMT2AL3MBTL1MAPT | |
| SCHEMBL22639870 | 0.99 | ACE2 (0.82) | SMN1; SMN2ACE2KMT2AL3MBTL1MAPT | |
| SCHEMBL30001091 | 0.99 | ACE2 (0.82) | SMN1; SMN2ACE2KMT2AL3MBTL1MAPT | |
| SCHEMBL31537007 | 0.88 | ACE2 (1.00) | SMN1; SMN2ACE2L3MBTL1TSHRGAA | |
| SCHEMBL31537006 | 0.88 | ACE2 (1.00) | SMN1; SMN2ACE2L3MBTL1TSHRGAA | |
| SCHEMBL22875771 | 0.88 | ACE2 (1.00) | SMN1; SMN2ACE2L3MBTL1TSHRGAA | |
| SCHEMBL24322624 | 0.88 | L3MBTL1 (0.72) | SMN1; SMN2ACE2KMT2AL3MBTL1MAPT | |
| SCHEMBL16371035 | 0.88 | L3MBTL1 (0.97) | SMN1; SMN2ACE2KMT2AL3MBTL1MAPT | |
| SCHEMBL30416315 | 0.88 | L3MBTL1 (0.97) | SMN1; SMN2ACE2KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831584-B | Targeted drug rescue with novel compositions, combinations and methods thereof | 埃克塞瓦有限责任公司 | 2023-03-10 | — | — | CN | disclosed |
| US-11478467-B2 | Targeted drug rescue with novel compositions, combinations, and methods thereof | Exciva GmbH (DE) | 2022-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11478467-B2 | Targeted drug rescue with novel compositions, combinations, and methods thereof | HTR2A, HTR2C, CYP3A43 | SMN1; SMN2 955/4885ACE2 449/4885KMT2A 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.