Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2097244 | 0.69 | DCUN1D1 (0.41) | CYP1A2CYP2C9CYP2C19KDM4ELMNA | |
| SCHEMBL7358537 | 0.67 | GAA (0.42) | CYP1A2KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL7700673 | 0.67 | ALDH1A1 (0.46) | HTR6KDM4ETDP1LMNAMAPT | |
| (Phenylsulfonyl)Benzene SCHEMBL2148473 | 0.66 | HTR6 (0.82) | HTR6TDP1MAPTALDH1A1HSD17B10 | |
| (Phenylsulfonyl)Benzene SCHEMBL4982378 | 0.64 | HTR6 (0.88) | HTR6TDP1MAPTALDH1A1PKM | |
| (Phenylsulfonyl)Benzene SCHEMBL29473549 | 0.63 | HTR6 (1.00) | HTR6CYP3A4TDP1MAPTALDH1A1 | |
| (Phenylsulfonyl)Benzene SCHEMBL13735236 | 0.63 | HTR6 (1.00) | HTR6CYP3A4TDP1MAPTALDH1A1 | |
| (Phenylsulfonyl)Benzene SCHEMBL29775288 | 0.63 | HTR6 (1.00) | HTR6CYP3A4TDP1MAPTALDH1A1 | |
| (Phenylsulfonyl)Benzene SCHEMBL29450723 | 0.63 | HTR6 (1.00) | HTR6CYP3A4TDP1MAPTALDH1A1 | |
| (Phenylsulfonyl)Benzene SCHEMBL30255 | 0.63 | HTR6 (1.00) | HTR6CYP3A4TDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9316633-B2 | Methods for identifying inhibitors of solute transporters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-04-19 | — | — | US | disclosed |
| US-20100190796-A1 | METHODS FOR IDENTIFYING INHIBITORS OF SOLUTE TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190796-A1 | METHODS FOR IDENTIFYING INHIBITORS OF SOLUTE TRANSPORTERS | SLC2A1, SLC2A3, SLC2A8 | HTR6 3146/4885CYP1A2 4752/4885CYP3A4 4323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.