SCHEMBL31521282

SCHEMBL31521282

Clc1cnc(Br)c2ccnn12

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.35
DGAT1 O75907 1/20 0.32
MALT1 Q9UDY8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23628601 0.72 PDE10A (0.37) PDE10A
SCHEMBL25346697 0.69 DGAT1 (0.32) PDE10ADGAT1
SCHEMBL25346629 0.61
SCHEMBL25345234 0.61 DGAT1 (0.38) DGAT1
SCHEMBL17687704 0.61 MAP4K4 (0.34)
SCHEMBL31521324 0.60 PDE10A (0.34) PDE10A
SCHEMBL24969531 0.60 EGLN1 (0.31)
SCHEMBL20400364 0.59 PDE10A (0.33) PDE10A
SCHEMBL31329875 0.59 PDE10A (0.33) PDE10A
SCHEMBL24387027 0.59 PDE10A (0.44) PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096957-A1 RAS-PI3K INHIBITORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed