SCHEMBL351192

SCHEMBL351192

COC(=O)C(=O)CC(C)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.52
GAA P10253 1/20 0.52
SI P14410 1/20 0.52
MGAM2 Q2M2H8 1/20 0.52
ALDH1A1 P00352 5/20 0.46
EGLN1 Q9GZT9 2/20 0.37
TET2 Q6N021 1/20 0.37
TSHR P16473 3/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 2/20 0.35
KDM6B O15054 1/20 0.35
KDM5C P41229 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
HSD17B10 Q99714 1/20 0.33
TRPA1 O75762 1/20 0.33
TGFBR1 P36897 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8804004 0.84 ALDH1A1 (0.45) MGAMGAASIMGAM2ALDH1A1
SCHEMBL1983275 0.80 MGAM (0.43) MGAMGAASIMGAM2ALDH1A1
SCHEMBL13478059 0.80 ALDH1A1 (0.43) MGAMGAASIMGAM2ALDH1A1
SCHEMBL28794549 0.80 MGAM (0.43) MGAMGAASIMGAM2ALDH1A1
SCHEMBL23408326 0.79 MGAM (0.44) MGAMGAASIMGAM2ALDH1A1
SCHEMBL27508659 0.79 ALDH1A1 (0.50) MGAMGAASIMGAM2ALDH1A1
SCHEMBL12533440 0.78 MGAM (0.42) MGAMGAASIMGAM2ALDH1A1
SCHEMBL7636706 0.78 ALDH1A1 (0.55) MGAMGAASIMGAM2ALDH1A1
SCHEMBL16634434 0.78 ALDH1A1 (0.45) MGAMGAASIMGAM2ALDH1A1
SCHEMBL28785847 0.78 MGAM (0.42) MGAMGAASIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116970746-A Synthetic tanning agent containing hexabasic carbonyl and preparation method and application thereof 南京工业大学 2023-10-31 CN claimed
CN-116356085-A Aliphatic synthetic tanning agent containing hexabasic carbonyl and preparation method and application thereof 南京工业大学 2023-06-30 CN claimed
CN-116334320-A Aliphatic synthetic tanning agent containing multifunctional groups and preparation method and application thereof 南京工业大学 2023-06-27 CN claimed
CN-116219085-A Synthetic tanning agent containing multifunctional structure and preparation method and application thereof 南京工业大学 2023-06-06 CN claimed
US-12378234-B2 Crystalline polymorphs of a 1-thiazol-2-yl-pyrazole-5-carboxylic acid derivative BANTAM PHARMACEUTICAL, LLC (US) 2025-08-05 US disclosed
US-12251372-B2 Antileishmanial compounds, compositions and use thereof TRUSTEES OF BOSTON UNIVERSITY 2025-03-18 US disclosed
CN-118638119-B Pyrazole purine herbicide safener as well as preparation method and application thereof 东北农业大学 2025-02-28 CN disclosed
US-12150934-B2 Methods of using substituted pyrazole and pyrazole compounds and for treatment of hyperproliferative diseases BANTAM PHARMACEUTICAL, LLC (US) 2024-11-26 US disclosed
CN-118638119-A Pyrazole purine herbicide safener as well as preparation method and application thereof 东北农业大学 2024-09-13 CN disclosed
CN-116356085-B Aliphatic synthetic tanning agent containing hexabasic carbonyl and preparation method and application thereof 南京工业大学 2024-08-16 CN disclosed
US-20240240077-A1 COLOR CONVERSION COMPOSITION, COLOR CONVERSION FILM, LIGHT SOURCE UNIT, DISPLAY, AND LIGHTING INCLUDING SAME, AND COMPOUND TORAY INDUSTRIES, INC. (JP) 2024-07-18 US disclosed
CN-116219085-B Synthetic tanning agent containing multifunctional structure and preparation method and application thereof 南京工业大学 2024-03-15 CN disclosed
EP-0915700-A1 USE OF BETA-SHEET MIMETICS AS PROTEASE AND KINASE INHIBITORS AND AS INHIBITORS OF TRANSCRIPTION FACTORS MOLECUMETICS, LTD. (US) 1999-05-19 EP disclosed
US-5859007-A TREATMENT OF DIABETES, OBESITY GLAXO WELLCOME INC. (US) 1999-01-12 US disclosed
WO-1998054246-A1 β-KETOESTERS FOR USE AS POLYMER STABILISERS AKCROS CHEMICALS (GB) 1998-12-03 WO disclosed
EP-0881253-A1 B-ketoesters for use as polymer stabilisers AKCROS CHEMICALS (GB) 1998-12-02 EP disclosed
WO-1998005333-A1 USE OF BETA-SHEET MIMETICS AS PROTEASE AND KINASE INHIBITORS AND AS INHIBITORS OF TRANSCRIPTION FACTORS MOLECUMETICS LTD. (US) 1998-02-12 WO disclosed
EP-0755384-A1 CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES GLAXO WELLCOME INC. (US) 1997-01-29 EP disclosed
WO-1995028391-A1 CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES GLAXO WELLCOME INC. (US) 1995-10-26 WO disclosed
EP-0372470-A2 Novel alpha-cyano-beta-oxopropionamides CIBA-GEIGY AG (CH) 1990-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240240077-A1 COLOR CONVERSION COMPOSITION, COLOR CONVERSION FILM, LIGHT SOURCE UNIT, DISPLAY, AND LIGHTING INCLUDING SAME, AND COMPOUND CDYL, ZKSCAN2, CAD MGAM 518/4885GAA 659/4885SI 2915/4885
US-12251372-B2 Antileishmanial compounds, compositions and use thereof MPO, SSB, SGMS2 MGAM 99/4885GAA 111/4885SI 1705/4885
US-12150934-B2 Methods of using substituted pyrazole and pyrazole compounds and for treatment of hyperproliferative diseases KRAS, TP53, CCNA1 MGAM 4592/4885GAA 2623/4885SI 3557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.