Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3089977 | 0.88 | BCL2L2 (0.50) | DPP4DPP8CYP3A4DPP9CYP1A2 | |
| SCHEMBL3595932 | 0.86 | DPP4 (0.49) | DPP4DPP8CYP3A4DPP9MEN1 | |
| SCHEMBL3605710 | 0.85 | MEN1 (0.40) | DPP4DPP8CYP3A4DPP9MEN1 | |
| SCHEMBL3088192 | 0.83 | DPP4 (0.46) | DPP4DPP8CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL3091438 | 0.82 | CXCR2 (0.51) | DPP4DPP8DPP9TSHRBCL2L2 | |
| SCHEMBL3605962 | 0.81 | DPP4 (0.41) | DPP4DPP8MEN1KMT2ABCL2L2 | |
| SCHEMBL3084277 | 0.80 | DPP4 (0.43) | DPP4DPP8CYP3A4DPP9HSP90AA1 | |
| SCHEMBL3595753 | 0.79 | DPP4 (0.47) | DPP4DPP8CYP3A4DPP9MEN1 | |
| SCHEMBL3084580 | 0.78 | DPP4 (0.49) | DPP4DPP8CYP3A4 | |
| SCHEMBL3084453 | 0.78 | CNR1 (0.45) | DPP4DPP8CYP3A4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |