Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4206068 | 0.92 | CCR5 (0.59) | CCR5 | |
| SCHEMBL4208132 | 0.92 | CCR5 (0.69) | CCR5 | |
| SCHEMBL5572556 | 0.82 | GPR119 (0.47) | CCR5 | |
| SCHEMBL5572558 | 0.82 | GPR119 (0.47) | CCR5 | |
| SCHEMBL14184998 | 0.81 | CCR5 (1.00) | CCR5 | |
| SCHEMBL4552609 | 0.81 | CCR5 (0.45) | CCR5 | |
| SCHEMBL3758660 | 0.81 | CCR5 (0.56) | CCR5 | |
| SCHEMBL3758664 | 0.81 | CCR5 (0.56) | CCR5 | |
| SCHEMBL4551923 | 0.81 | CCR5 (0.65) | CCR5 | |
| SCHEMBL5576089 | 0.80 | CCR5 (0.54) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088860-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008070758-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |