Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 15/20 | 0.51 |
| ▸ | BRAF | P15056 | 15/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | TEK | Q02763 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4417623 | 0.94 | TEK (0.51) | RAF1BRAFCSF1RTEK | |
| SCHEMBL4417393 | 0.93 | TEK (0.50) | RAF1BRAFCSF1RTEK | |
| SCHEMBL5593317 | 0.92 | CSF1R (0.48) | RAF1BRAFCSF1RTEK | |
| SCHEMBL4411177 | 0.92 | CSF1R (0.45) | RAF1BRAFCSF1RTEK | |
| SCHEMBL5622327 | 0.89 | RAF1 (0.48) | RAF1BRAFCSF1RTEK | |
| SCHEMBL5593313 | 0.87 | TEK (0.52) | RAF1BRAFTEK | |
| SCHEMBL5593338 | 0.86 | RAF1 (0.44) | RAF1BRAFCSF1RTEK | |
| SCHEMBL14473152 | 0.86 | CSF1R (0.46) | RAF1BRAFCSF1RTEK | |
| SCHEMBL4415077 | 0.84 | RAF1 (0.52) | RAF1BRAFCSF1R | |
| SCHEMBL14473153 | 0.84 | TEK (0.53) | RAF1BRAFCSF1RTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035005-A2 | THERAPY USING CYTOKINE INHIBITORS | Kemia, INC. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146712-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-12-21 | — | — | WO | disclosed |