Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610291 | 0.91 | LMNA (0.44) | HSD17B10CYP3A4MMP13MMP14ALDH1A1 | |
| SCHEMBL4610084 | 0.88 | CXCR3 (0.48) | HSD17B10KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4611167 | 0.87 | HSD17B10 (0.60) | HSD17B10KDM4EALDH1A1LMNAGLA | |
| SCHEMBL4610253 | 0.82 | MAPT (0.49) | MMP13ALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL4609903 | 0.81 | SMN1; SMN2 (0.38) | HSD17B10LMNAPKMDPP4DPP9 | |
| SCHEMBL6783038 | 0.80 | MMP13 (0.42) | CYP3A4MMP13MMP14LMNATP53 | |
| SCHEMBL4609998 | 0.80 | GRM5 (0.47) | HSD17B10KDM4EALDH1A1LMNAPKM | |
| SCHEMBL6783034 | 0.80 | MMP13 (0.42) | CYP3A4MMP13MMP14LMNATP53 | |
| SCHEMBL4612472 | 0.79 | HSD17B10 (0.49) | HSD17B10KDM4EALDH1A1LMNAGLA | |
| SCHEMBL4610349 | 0.79 | MAPK1 (0.47) | HSD17B10CYP3A4MMP13ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641771-B1 | HYDROXAMATE SULFONAMIDES AS CD23 SHEDDING INHIBITORS | UCB PHARMA SA (BE) | 2008-10-15 | — | — | EP | disclosed |