Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 7/20 | 0.63 |
| ▸ | FDPS | P14324 | 11/20 | 0.61 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21879326 | 1.00 | GGPS1 (0.63) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL20484187 | 1.00 | GGPS1 (0.63) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL4735538 | 1.00 | GGPS1 (0.63) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL9463628 | 1.00 | GGPS1 (0.63) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL8645576 | 1.00 | GGPS1 (0.63) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL6229883 | 1.00 | GGPS1 (0.63) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL3621873 | 0.98 | FDPS (0.59) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL21101802 | 0.91 | GGPS1 (0.68) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL6896582 | 0.91 | GGPS1 (0.68) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL11406652 | 0.91 | GGPS1 (0.68) | GGPS1FDPSSMPD1LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411032-B1 | PLANT EXTRACTS FOR THE TREATMENT OF SKIN DISEASES | EVORIA GMBH (DE) | 2014-07-09 | — | — | EP | disclosed |
| EP-2411032-A2 | PLANT EXTRACTS FOR TREATING SKIN DISEASES | Evoria GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108488-A2 | PLANT EXTRACTS FOR TREATING SKIN DISEASES | EVORIA GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |