SCHEMBL4850806

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16957840	0.79	ACHE (0.54)	ACHEALDH1A1CYP3A4PTGDR2L3MBTL1
	SCHEMBL4852766	0.77	TRPA1 (0.41)	ALDH1A1L3MBTL1KMT2AMEN1HSD17B10
	SCHEMBL4850352	0.77	DRD2 (0.37)	PTGDR2L3MBTL1
	SCHEMBL11164868	0.76	PTGDR2 (0.57)	ACHEALDH1A1CYP3A4PTGDR2L3MBTL1
	SCHEMBL10534970	0.75	PTGDR2 (0.60)	ACHEALDH1A1CYP3A4PTGDR2L3MBTL1
	SCHEMBL4856372	0.72	CYP3A4 (0.38)	ALDH1A1CYP3A4KMT2AMEN1TSHR
	SCHEMBL1266168	0.72	HTR2C (0.63)	—
	SCHEMBL14781348	0.69	ACHE (0.50)	ACHEALDH1A1CYP3A4L3MBTL1KMT2A
	SCHEMBL24624424	0.69	ACHE (0.39)	ACHEALDH1A1CYP3A4L3MBTL1TSHR
	SCHEMBL4859356	0.68	HTR3A (0.48)	CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.