⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529109 | 0.76 | — | — | |
| SCHEMBL142963 | 0.74 | — | — | |
| SCHEMBL7070827 | 0.70 | — | — | |
| SCHEMBL12720216 | 0.70 | — | — | |
| SCHEMBL13242309 | 0.70 | — | — | |
| SCHEMBL12461568 | 0.70 | — | — | |
| SCHEMBL12670153 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL29199515 | 0.68 | — | — | |
| SCHEMBL13018309 | 0.68 | — | — | |
| Ammonia Solution, Strong SCHEMBL8894174 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794122-A1 | 3-SUBSTITUTED-5- AND 6-AMINOALKYL INDOLE-2-CARBOXYLIC ACID AMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I | Aventis Pharmaceuticals, Inc. (US) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006023467-A1 | 3-SUBSTITUTED-5- AND 6-AMINOALKYL INDOLE-2-CARBOXYLIC ACID AMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I&epsiv; | AVENTIS PHARMACEUTICALS INC. (US) | 2006-03-02 | — | — | WO | disclosed |
| EP-0876161-B1 | CONTRAST MEDIA | NYCOMED SALUTAR INC (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-0876161-A2 | CONTRAST MEDIA | NYCOMED SALUTAR, INC. (US) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997026921-A2 | CONTRAST MEDIA | NYCOMED SALUTAR INC. (US) | 1997-07-31 | — | — | WO | disclosed |