Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 12/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6071803 | 0.86 | KDM4E (0.45) | DPP4DPP8DPP7KDM4ESLC18A3 | |
| Trifluoroacetic Acid SCHEMBL6071920 | 0.83 | HSD11B1 (0.53) | DPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL6072071 | 0.82 | SLC18A3 (0.62) | SLC18A3MAPK1 | |
| Trifluoroacetic Acid SCHEMBL6072183 | 0.79 | GPR6 (0.50) | KDM4ECYP2C19MAPK1 | |
| Trifluoroacetic Acid SCHEMBL6071612 | 0.79 | SLC18A3 (0.54) | CYP2C19SLC18A3SLC6A7MAPK1 | |
| Trifluoroacetic Acid SCHEMBL6071855 | 0.79 | SLC18A3 (0.45) | DPP4KCNH2KDM4ECYP2C19SLC18A3 | |
| Trifluoroacetic Acid SCHEMBL6071718 | 0.78 | MAPT (0.52) | DPP4DPP8DPP7KDM4ECYP2C19 | |
| Trifluoroacetic Acid SCHEMBL6071717 | 0.78 | TTR (0.46) | FAAHSLC18A3 | |
| Trifluoroacetic Acid SCHEMBL5814484 | 0.78 | TTR (0.46) | FAAHSLC18A3 | |
| Trifluoroacetic Acid SCHEMBL3096799 | 0.78 | HTR3E (0.43) | KCNH2KDM4ESLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | ACKR3, CCR5, CXCR2 | FAAH 1368/4885MGLL 2345/4885DPP4 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.