Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 14/20 | 0.39 |
| ▸ | PPARA | Q07869 | 8/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168010 | 0.91 | PPARD (0.40) | PPARDPPARAPPARGHIF1AEPAS1 | |
| SCHEMBL6164704 | 0.87 | PPARD (0.56) | PPARDPPARAPPARG | |
| Hydrochloric Acid SCHEMBL5861139 | 0.87 | PPARD (0.55) | PPARDPPARAPPARG | |
| SCHEMBL6167938 | 0.85 | PPARD (0.41) | PPARDPPARAPPARG | |
| SCHEMBL5860888 | 0.84 | PPARD (0.43) | PPARDPPARAPPARG | |
| SCHEMBL6166173 | 0.80 | HIF1A (0.46) | HIF1AEPAS1MAPK1CYP3A4CYP2C19 | |
| SCHEMBL6164052 | 0.79 | PPARD (0.44) | PPARDPPARAPPARG | |
| SCHEMBL6164370 | 0.78 | PPARD (0.41) | PPARDPPARAPPARG | |
| SCHEMBL6167418 | 0.77 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL6167228 | 0.77 | PPARD (0.49) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | claimed |