Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200560 | 0.86 | GAA (0.52) | GAAALDH1A1CYP1A2CYP3A4ALOX12 | |
| SCHEMBL6198193 | 0.81 | EGLN1 (0.54) | GAAALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6200932 | 0.79 | GAA (0.41) | GAAALDH1A1CYP1A2CYP3A4ALOX12 | |
| SCHEMBL6199743 | 0.77 | GAA (0.44) | GAAALDH1A1CYP1A2CYP3A4ALOX12 | |
| SCHEMBL6198567 | 0.76 | GAA (0.43) | GAAALDH1A1CYP1A2CYP3A4ALOX12 | |
| SCHEMBL6198572 | 0.74 | PTGS2 (0.44) | GAAALDH1A1CYP1A2CYP3A4ALOX12 | |
| SCHEMBL27487163 | 0.74 | HAVCR2 (0.47) | ALDH1A1ALOX12LMNAMAPTTDP1 | |
| SCHEMBL21261424 | 0.74 | GAA (0.71) | GAAALDH1A1CYP1A2CYP3A4ALOX12 | |
| SCHEMBL6198610 | 0.69 | EGLN1 (0.56) | GAAALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6198755 | 0.69 | POLA1 (0.57) | ALDH1A1CYP1A2CYP3A4CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |