Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 7/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.52 |
| ▸ | ITGAL | P20701 | 7/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.39 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568833 | 0.87 | ITGB2 (0.52) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL6817329 | 0.87 | ITGB2 (0.52) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL6312254 | 0.85 | ITGB2 (0.53) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL6310553 | 0.85 | ITGAL (0.49) | ITGB2ICAM1ITGALHSD11B1PDE7A | |
| SCHEMBL6198648 | 0.82 | ITGB2 (0.47) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL4278725 | 0.81 | ITGAL (0.67) | ITGB2ICAM1ITGALHTTMAPT | |
| SCHEMBL4278719 | 0.81 | ITGAL (0.67) | ITGB2ICAM1ITGALHTTMAPT | |
| SCHEMBL6493194 | 0.79 | ITGAL (0.73) | ITGB2ICAM1ITGAL | |
| SCHEMBL6493588 | 0.79 | ITGAL (0.73) | ITGB2ICAM1ITGAL | |
| SCHEMBL6316878 | 0.78 | ITGB2 (0.43) | ITGB2ICAM1ITGALEIF2AK2CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |