Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973656 | 0.92 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| SCHEMBL23421740 | 0.92 | ZDHHC20 (0.49) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| SCHEMBL36287 | 0.89 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| SCHEMBL22640918 | 0.88 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| Hydrogen Sulfide SCHEMBL27807905 | 0.87 | ZDHHC20 (0.49) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| SCHEMBL2560026 | 0.85 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| SCHEMBL29147652 | 0.84 | ZDHHC20 (0.44) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| SCHEMBL20459785 | 0.84 | ZDHHC20 (0.44) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| Ethylene Glycol SCHEMBL28659119 | 0.83 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2TSHRMAPK1CA12 | |
| SCHEMBL23421037 | 0.83 | ZDHHC20 (0.54) | ZDHHC20ZDHHC2TSHRMAPK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005054548-A2 | METHODS, COMPOSITIONS, AND KITS FOR PROTEIN CRYSTALLIZATION | INVITROGEN CORPORATION (US) | 2005-06-16 | — | — | WO | disclosed |