Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 5/20 | 0.40 |
| ▸ | PPIB | P23284 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | PPIG | Q13427 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777224 | 0.85 | EPHX1 (0.37) | ALDH1A1GAAKMT2ATLR7HPGD | |
| SCHEMBL6780666 | 0.83 | TLR7 (0.37) | TLR7KDM4E | |
| SCHEMBL6284008 | 0.83 | TLR7 (0.33) | ALDH1A1LMNATLR7 | |
| SCHEMBL6777774 | 0.82 | TLR7 (0.41) | PPIDPPIBPPIAPPIGTLR7 | |
| SCHEMBL6110335 | 0.81 | KDM4E (0.39) | ALDH1A1GAATLR7HPGDKDM4E | |
| SCHEMBL6777793 | 0.81 | PKM (0.35) | TLR7PKM | |
| SCHEMBL6775775 | 0.81 | EPHX1 (0.37) | ALDH1A1GAAKMT2ATLR7HPGD | |
| Hydrochloric Acid SCHEMBL6110768 | 0.80 | KDM4E (0.38) | ALDH1A1GAATLR7HPGDKDM4E | |
| SCHEMBL6771859 | 0.79 | FAAH (0.36) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL6096758 | 0.78 | MEN1 (0.42) | ALDH1A1GAAKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |