Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 2/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2565236 | 0.87 | BCAT2 (0.56) | CNR2LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL6803972 | 0.86 | DHODH (0.60) | LMNAALDH1A1MAPTL3MBTL1TDP1 | |
| SCHEMBL6638818 | 0.85 | KMO (0.55) | LMNAALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL6637186 | 0.84 | ALDH1A1 (0.47) | LMNAALDH1A1MAPTL3MBTL1HPGD | |
| SCHEMBL25206256 | 0.80 | CNR2 (0.45) | CNR2ALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL15560003 | 0.79 | KMT2A (0.68) | LMNAALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL10690677 | 0.79 | PRKDC (0.64) | LMNAALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL30292805 | 0.78 | HNF4A (0.63) | ALDH1A1KDM4EHPGDHSD17B10CYP2C9 | |
| SCHEMBL18759613 | 0.78 | HNF4A (0.63) | ALDH1A1KDM4EHPGDHSD17B10CYP2C9 | |
| SCHEMBL28090800 | 0.77 | BCAT2 (0.64) | LMNAALDH1A1MAPK1POLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | CNR2 49/4885LMNA 956/4885ALDH1A1 2901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.