Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972239 | 1.00 | HIF1A (0.41) | HIF1AMAPTTSHRCES2ACHE | |
| SCHEMBL27446293 | 0.74 | TSHR (0.50) | HIF1AMAPTTSHRCES2CES1 | |
| SCHEMBL695709 | 0.74 | MAPT (0.36) | MAPT | |
| SCHEMBL695710 | 0.74 | MAPT (0.36) | MAPT | |
| SCHEMBL7457347 | 0.74 | TSHR (0.50) | HIF1AMAPTTSHRCES2CES1 | |
| SCHEMBL696851 | 0.74 | MAPT (0.36) | MAPT | |
| SCHEMBL51251 | 0.73 | TSHR (0.48) | MAPTTSHR | |
| SCHEMBL6963751 | 0.71 | HIF1A (0.37) | HIF1AMAPTTSHR | |
| SCHEMBL6963747 | 0.71 | HIF1A (0.37) | HIF1AMAPTTSHR | |
| SCHEMBL6968615 | 0.71 | KDM4E (0.34) | MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |