SCHEMBL727205

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3814425	0.85	BCHE (0.44)	HTR2AHTR7DRD2HTR6PKM
	SCHEMBL14516490	0.82	TLR7 (0.41)	ALDH1A1
	SCHEMBL14516480	0.82	SIGMAR1 (0.40)	HTR7HTR6ALDH1A1POLB
	SCHEMBL14516479	0.82	BCHE (0.40)	HTR7DRD2HTR6ALDH1A1CCR1
	SCHEMBL14516484	0.82	BCHE (0.49)	HTR2AHTR7PKMALDH1A1HTT
	SCHEMBL14516487	0.82	ALDH1A1 (0.38)	ALDH1A1POLB
	SCHEMBL6779047	0.82	CYP2C9 (0.43)	HTR2AHTR7DRD2HTR6CYP2D6
	SCHEMBL14516489	0.82	HTR7 (0.47)	HTR2AHTR7DRD2HTR6CYP2C9
	SCHEMBL727248	0.81	HTR7 (0.52)	HTR2AHTR7HTR6TSHRALDH1A1
	SCHEMBL14516483	0.80	LMNA (0.45)	ALDH1A1MAPK1GAAPOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.