Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | EPOR | P19235 | 6/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447529 | 0.90 | TPSAB1 (0.50) | TPSAB1TPSD1TPSG1CPB1CPB2 | |
| SCHEMBL28477064 | 0.84 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1EPOR | |
| SCHEMBL28477062 | 0.84 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1EPOR | |
| SCHEMBL5692891 | 0.82 | EPOR (0.55) | TPSAB1TPSD1TPSG1CPB1CPB2 | |
| SCHEMBL3820596 | 0.82 | TPSAB1 (0.53) | TPSAB1TPSD1TPSG1CPB1CPB2 | |
| SCHEMBL4150947 | 0.82 | TPSAB1 (0.53) | TPSAB1TPSD1TPSG1CPB1CPB2 | |
| SCHEMBL375887 | 0.82 | TPSAB1 (0.53) | TPSAB1TPSD1TPSG1CPB1CPB2 | |
| SCHEMBL7785339 | 0.82 | TPSAB1 (0.47) | TPSAB1TPSD1TPSG1CPB1CPB2 | |
| SCHEMBL4848148 | 0.82 | CPB1 (0.49) | TPSAB1TPSD1TPSG1CPB1CPB2 | |
| SCHEMBL10877450 | 0.81 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1CPB1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552264-A1 | N-(2-ALKYL-3-MERCAPTOGLUTARYL)-AMINO-DIAZA CYCLOALKANONE DERIVATIVES AND THEIR USE AS COLLAGENASE INHIBITORS | BEECHAM GROUP plc (GB) | 1993-07-28 | — | — | EP | disclosed |
| WO-1992006966-A1 | N-(2-ALKYL-3-MERCAPTOGLUTARYL)-AMINO-DIAZA CYCLOALKANONE DERIVATIVES AND THEIR USE AS COLLAGENASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1992-04-30 | — | — | WO | disclosed |