Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353849 | 0.94 | NPC1 (0.37) | NPC1RAB9APOLBLMNACYP3A4 | |
| SCHEMBL769514 | 0.94 | NPC1 (0.37) | NPC1RAB9APOLBLMNACYP3A4 | |
| SCHEMBL1499910 | 0.89 | NPC1 (0.45) | NPC1RAB9APOLBLMNACYP3A4 | |
| SCHEMBL5834165 | 0.88 | NPC1 (0.33) | NPC1RAB9APOLBLMNA | |
| SCHEMBL5834029 | 0.88 | PTGS2 (0.38) | NPC1RAB9APOLBLMNACYP3A4 | |
| SCHEMBL769171 | 0.88 | NPC1 (0.36) | NPC1RAB9APOLBLMNACYP3A4 | |
| SCHEMBL29358608 | 0.88 | NPC1 (0.36) | NPC1RAB9APOLBLMNACYP3A4 | |
| SCHEMBL7901461 | 0.86 | NPC1 (0.41) | NPC1RAB9APOLBLMNACYP3A4 | |
| SCHEMBL30423445 | 0.86 | NPC1 (0.35) | NPC1RAB9APOLBLMNACYP3A4 | |
| SCHEMBL5834169 | 0.85 | CNR1 (0.37) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268415-B1 | POLYMERS AND STABILIZERS FOR ENHANCED STABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-31 | — | — | US | claimed |
| US-6268415-B1 | POLYMERS AND STABILIZERS FOR ENHANCED STABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-31 | — | — | US | disclosed |
| US-6268415-B1 | POLYMERS AND STABILIZERS FOR ENHANCED STABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-31 | — | — | US | disclosed |
| US-6187845-B1 | LAMINATION OR MULTILAYER STRUCTURE | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-02-13 | — | — | US | disclosed |