Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | CA12 | O43570 | 6/20 | 0.50 |
| ▸ | CA9 | Q16790 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 6/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31619033 | 0.88 | NPC1 (0.52) | NPC1MTORRAB9ACA2CA12 | |
| SCHEMBL28281697 | 0.86 | PKM (0.47) | NPC1MTORRAB9ACA2CA12 | |
| SCHEMBL28705803 | 0.86 | CA12 (0.50) | NPC1MTORRAB9ACA2CA12 | |
| SCHEMBL28715043 | 0.86 | NPC1 (0.50) | NPC1MTORRAB9ACA2CA12 | |
| SCHEMBL28281734 | 0.86 | NPC1 (0.46) | NPC1MTORRAB9ACA2CA12 | |
| SCHEMBL28710707 | 0.86 | NPC1 (0.46) | NPC1MTORRAB9ACA2CA12 | |
| SCHEMBL28858455 | 0.86 | NPC1 (0.55) | NPC1MTORRAB9ACA2CA12 | |
| SCHEMBL28281703 | 0.86 | NPC1 (0.46) | NPC1MTORRAB9ACA2CA12 | |
| SCHEMBL28712504 | 0.82 | NPC1 (0.50) | NPC1MTORRAB9ACA2CA12 | |
| SCHEMBL28708712 | 0.82 | HSD11B1 (0.44) | NPC1MTORRAB9ACA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195687-B | Beta-chloro tetra-substituted alkenyl sulfone compound and synthesis method thereof | 华南理工大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-114195687-A | Beta-chloro tetra-substituted alkenyl sulfone compound and synthetic method thereof | 华南理工大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-111302986-B | Preparation method of naphthol-based sulfone compound | 佛山科学技术学院 | 2020-08-18 | — | — | CN | disclosed |
| CN-111302986-A | Preparation method of naphthol-based sulfone compound | 佛山科学技术学院 | 2020-06-19 | — | — | CN | disclosed |
| CN-109456237-A | The synthetic method of alkynyl sulfone | 怀化学院 | 2019-03-12 | — | — | CN | disclosed |
| CN-109096214-A | A kind of preparation method of the novel trisubstituted 1,2,3- triazole of 4- sulfonyl -1,4,5- | 大连理工大学 | 2018-12-28 | — | — | CN | disclosed |
| US-7635181-B2 | Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same | FUJIFILM CORPORATION (JP) | 2009-12-22 | — | — | US | disclosed |
| US-7306894-B2 | Polymerizable composition, photopolymerizing method and process for producing lithographic printing plate using the polymerizable composition | FUJIFILM CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-6255490-B1 | TREATING DISORDERS ASSOCIATED WITH CHANGES IN CHOLINERGIC ACTIVITY; NON-OPIATE BASED ANALGESIC FOR MODERATE TO SEVERE PAIN EQUALLY OR EXCEEDING THE POTENCY OF OPIATE ANALGESICS, YET LACKING ADDICTIVE SIDE EFFECTS | UNIVERSITY OF VIRGINIA | 2001-07-03 | — | — | US | disclosed |
| US-6117889-A | 7-Azabicyclo-[2.2.1]-heptane and -heptene derivatives as analgesics and anti-inflammatory agents | UNIVERSITY OF VIRGINIA (US) | 2000-09-12 | — | — | US | disclosed |
| US-6060473-A | 7-azabicyclo[2.2.1]-heptane and -heptene derivatives as cholinergic receptor ligands | UCB S.A. - DTB (BE) | 2000-05-09 | — | — | US | disclosed |
| EP-0778835-A4 | 7-AZABICYCLO 2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS CHOLINERGIC RECEPTOR LIGANDS | UNIV VIRGINIA (US) | 1999-02-03 | — | — | EP | disclosed |
| US-5817679-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | UNIVERSITY OF VIRGINIA (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0778835-A1 | 7-AZABICYCLO 2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS CHOLINERGIC RECEPTOR LIGANDS | UNIVERSITY OF VIRGINIA (US) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996006093-A1 | 7-AZABICYCLO[2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS CHOLINERGIC RECEPTOR LIGANDS | UNIVERSITY OF VIRGINIA (US) | 1996-02-29 | — | — | WO | disclosed |
| EP-0691971-A1 | 7-AZABICYCLO- 2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS ANALGESICS AND ANTI-INFLAMMATORY AGENTS | UNIVERSITY OF VIRGINIA (US) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022868-A1 | 7-AZABICYCLO-[2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS ANALGESICS AND ANTI-INFLAMMATORY AGENTS | UNIVERSITY OF VIRGINIA (US) | 1994-10-13 | — | — | WO | disclosed |
| US-4022804-A | ADDITION REACTION; SULFONIC ACID BROMIDES, UNSATURATED COMPOUNDS | BASF AKTIENGESELLSCHAFT (DT) | 1977-05-10 | — | — | US | disclosed |