Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.41 |
| ▸ | PLAU | P00749 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 2/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079129 | 0.76 | THRA (0.44) | CSNK2A1PLAUMAPTHPGDMAPK1 | |
| SCHEMBL3119032 | 0.76 | CSNK2A1 (0.47) | CSNK2A1PLAUSMN1; SMN2NPC1HPGD | |
| SCHEMBL8069710 | 0.75 | CSNK2A1 (0.41) | CSNK2A1PLAUSMN1; SMN2MAPTHPGD | |
| Hydrochloric Acid SCHEMBL3110560 | 0.74 | CSNK2A1 (0.49) | CSNK2A1SMN1; SMN2NPC1HPGDGLA | |
| SCHEMBL6943761 | 0.71 | KDM4E (0.48) | CSNK2A1SMN1; SMN2LOXLOXL2KMT2A | |
| Hydrochloric Acid SCHEMBL3113761 | 0.70 | KDM4E (0.47) | CSNK2A1SMN1; SMN2LOXLOXL2KMT2A | |
| SCHEMBL506565 | 0.69 | KEAP1 (0.58) | SMN1; SMN2 | |
| SCHEMBL23573785 | 0.68 | CSNK2A1 (0.38) | CSNK2A1PLAUSMN1; SMN2MAPTHPGD | |
| SCHEMBL12958183 | 0.67 | LMNA (0.44) | CSNK2A1MAPTHPGDMAPK1L3MBTL1 | |
| SCHEMBL19598863 | 0.67 | CSNK2A1 (0.54) | CSNK2A1SMN1; SMN2NPC1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634403-B1 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO SPA (IT) | 2000-09-13 | — | — | EP | disclosed |
| US-5541214-A | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO S.P.A. (IT) | 1996-07-30 | — | — | US | disclosed |
| EP-0634403-A1 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO S.p.A. (IT) | 1995-01-18 | — | — | EP | disclosed |