Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.51 |
| ▸ | CRHR1 | P34998 | 6/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727614 | 0.87 | HSD11B1 (0.40) | HSD11B1CRHR1TNKSNR1H2NR1H3 | |
| SCHEMBL8876219 | 0.86 | CRHR1 (0.40) | HSD11B1CRHR1PDE2APDE10AKMT2A | |
| SCHEMBL8300288 | 0.85 | CRHR1 (0.37) | HSD11B1CRHR1LMNAPDE2APDE10A | |
| SCHEMBL8878103 | 0.84 | CRHR1 (0.41) | HSD11B1CRHR1LMNAHTTPDE2A | |
| SCHEMBL5727058 | 0.84 | HSD11B1 (0.36) | HSD11B1CRHR1NR1H2NR1H3PDE2A | |
| SCHEMBL5727128 | 0.84 | HSD11B1 (0.36) | HSD11B1CRHR1NR1H2NR1H3PDE2A | |
| SCHEMBL5726771 | 0.84 | HSD11B1 (0.36) | HSD11B1CRHR1NR1H2NR1H3PDE2A | |
| SCHEMBL8303712 | 0.83 | PDE2A (0.38) | HSD11B1CRHR1NR1H2NR1H3LMNA | |
| SCHEMBL8875200 | 0.83 | F7 (0.38) | HSD11B1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL8875632 | 0.82 | HSD11B1 (0.39) | HSD11B1CRHR1PDE2APTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648752-B1 | TRIAZOLE DERIVATIVE, INSECTICIDAL/ACARICIDAL AGENT, AND PROCESS FOR PRODUCING THE SAME | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5700824-A | Triazole derivatives, insecticide, acaricide and methods thereof | KUMIAI CHEMICAL INDUSTRIAL CO. LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5616594-A | Triazole derivatives, insecticide, acaricide and methods thereof | IHARA CHEMICAL INDUSTRY CO. LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0648752-A1 | TRIAZOLE DERIVATIVE, INSECTICIDAL/ACARICIDAL AGENT, AND PROCESS FOR PRODUCING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |