Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 8/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558001 | 0.91 | CTSA (0.41) | CTSAPTGS2GABRA2 | |
| SCHEMBL5732775 | 0.82 | PTGS2 (0.42) | CTSAPTGDR2PTGS2 | |
| SCHEMBL8559048 | 0.81 | PTGS2 (0.43) | CTSAPTGDR2PTGS2 | |
| SCHEMBL5732590 | 0.76 | PTGS2 (0.44) | CTSAPTGDR2PTGS2 | |
| SCHEMBL5733045 | 0.73 | DRD1 (0.40) | CTSAPTGS2 | |
| SCHEMBL6002182 | 0.72 | PTGS2 (0.41) | CTSAPTGS2 | |
| SCHEMBL6002011 | 0.70 | PTGS2 (0.40) | CTSAPTGS2 | |
| SCHEMBL5732778 | 0.70 | LNPEP (0.37) | — | |
| SCHEMBL5732159 | 0.68 | PTGS2 (0.46) | CTSAPTGS2 | |
| SCHEMBL8146329 | 0.68 | CTSK (0.47) | CTSATGFBR1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |