Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726410 | 0.93 | ALDH1A1 (0.40) | FFAR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL874031 | 0.93 | FFAR3 (0.43) | FFAR3ALDH1A1 | |
| SCHEMBL7739592 | 0.78 | ALDH1A1 (0.45) | FFAR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL1928676 | 0.73 | — | — | |
| SCHEMBL1938094 | 0.72 | — | — | |
| SCHEMBL17425036 | 0.71 | — | — | |
| SCHEMBL12910473 | 0.71 | HSD17B10 (0.42) | FFAR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL20599656 | 0.70 | FFAR3 (0.36) | FFAR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL1662191 | 0.69 | — | — | |
| SCHEMBL17958 | 0.69 | NPSR1 (0.52) | FFAR3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643000-A2 | THERAPEUTIC PIPERAZINES | Dart Neuroscience (Cayman) Ltd (KY) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012040258-A2 | THERAPEUTIC PIPERAZINES | HELICON THERAPEUTICS, INC. (US) | 2012-03-29 | — | — | WO | disclosed |