Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9077921 | 0.85 | KDM4E (0.33) | KDM4EALDH1A1GAACYP1A2CYP2C19 | |
| SCHEMBL9076935 | 0.84 | SMN1; SMN2 (0.40) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9078368 | 0.84 | KDM4E (0.32) | KDM4EALDH1A1GAACYP1A2CYP2C19 | |
| SCHEMBL10729447 | 0.83 | HTT (0.34) | KDM4EALDH1A1CYP1A2PKMKMT2A | |
| SCHEMBL4507444 | 0.81 | PDE4D (0.39) | KDM4EALDH1A1HTR2AHTR2CMEN1 | |
| SCHEMBL10724382 | 0.80 | PKM (0.34) | ALDH1A1PKMMEN1KMT2AHSD17B10 | |
| SCHEMBL8675021 | 0.79 | SMN1; SMN2 (0.33) | ALDH1A1KMT2AHPGD | |
| SCHEMBL8675019 | 0.79 | SMN1; SMN2 (0.33) | ALDH1A1KMT2AHPGD | |
| SCHEMBL8423375 | 0.79 | FGFR1 (0.34) | ALDH1A1CYP1A2PKMKMT2AHPGD | |
| SCHEMBL9078850 | 0.79 | KMO (0.33) | KDM4EALDH1A1CYP1A2CYP2C19PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282944-B1 | Pyrazole derivative and herbicide containing it | NISSAN CHEMICAL IND LTD (JP) | 1996-09-11 | — | — | EP | claimed |
| EP-0282944-A2 | Pyrazole derivative and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-09-21 | — | — | EP | claimed |