Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL693139 | 0.90 | CASP1 (0.61) | TRPA1PTGS1CACNA1CCYP1A2CYP2D6 | |
| SCHEMBL6933453 | 0.88 | TRPA1 (0.48) | TRPA1PTGS1CACNA1CCYP1A2CYP2D6 | |
| SCHEMBL6557093 | 0.87 | CASP1 (0.49) | TRPA1PTGS1CACNA1CCYP1A2CYP2D6 | |
| SCHEMBL453729 | 0.86 | TRPA1 (0.50) | TRPA1PTGS1CACNA1CCYP1A2CYP2D6 | |
| SCHEMBL11464121 | 0.83 | POLB (0.47) | CYP1A2KMT2AGAAALDH1A1TSHR | |
| SCHEMBL7688086 | 0.81 | CYP1A2 (0.57) | TRPA1PTGS1CACNA1CCYP1A2CYP2D6 | |
| SCHEMBL6932118 | 0.79 | ALDH1A1 (0.59) | TRPA1PTGS1CACNA1CCYP1A2CYP2D6 | |
| SCHEMBL11443273 | 0.78 | TDP1 (0.43) | CYP3A4MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3862347 | 0.78 | CASP1 (0.43) | TRPA1PTGS1CACNA1CCYP1A2CYP2D6 | |
| SCHEMBL6928569 | 0.77 | CYP1A2 (0.57) | TRPA1PTGS1CACNA1CCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1956 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144724-A1 | Mixture of at least five surfactants (I1) to (I5) | WELLA GERMANY GMBH (DE) | 2026-05-28 | — | — | US | claimed |
| US-12636241-B1 | Method and composition for oxidative hair coloring | WELLA OPERATIONS US LLC (US) | 2026-05-26 | — | — | US | claimed |
| WO-2026102602-A1 | COMPOSITION FOR DYEING KERATIN FIBERS | L'OREAL (FR) | 2026-05-21 | — | — | WO | claimed |
| EP-4731170-A1 | OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE | Wella Germany GmbH (DE) | 2026-04-29 | — | — | EP | claimed |
| US-12564545-B2 | Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents | WELLA GERMANY GMBH (DE) | 2026-03-03 | — | — | US | claimed |
| WO-2025242864-A1 | DISCOLORING COMPOSITION FOR KERATIN FIBERS DYED WITH BLEACH-STABLE DIRECT DYES | KAO CORPORATION (JP) | 2025-11-27 | — | — | WO | claimed |
| EP-4408377-B1 | COMPOSITION COMPRISING OXIDATIVE AND DIRECT DYES | KAO CORP (JP) | 2025-10-08 | — | — | EP | claimed |
| US-12396938-B2 | Compositions and methods for coloring hair | L'OREAL (FR) | 2025-08-26 | — | — | US | claimed |
| US-12383482-B2 | Hair coloring compositions | WELLA GERMANY GMBH (DE) | 2025-08-12 | — | — | US | claimed |
| EP-3393431-B1 | COMPOSITION FOR DYEING THE HAIR, COMPRISING AN OXIDATION BASE, A 2-AMINO-5-ETHYLPHENOL COUPLER AND A FATTY SUBSTANCE | OREAL (FR) | 2025-07-23 | — | — | EP | claimed |
| EP-1103248-B1 | Hair dyeing composition comprising N-ethyl-N-isopropyl-p-phenylenediamine | GOLDWELL GMBH (DE) | 2001-08-22 | — | — | EP | claimed |
| WO-2001054656-A1 | NOVEL PRIMARY INTERMEDIATE FOR USE IN OXIDATIVE HAIR DYEING | P&G-CLAIROL, INC. (US) | 2001-08-02 | — | — | WO | claimed |
| EP-1120105-A2 | 1-(2,5-diaminophenyl)ethanol and its use in oxidative hair dyeing | Bristol-Myers Squibb Company (US) | 2001-08-01 | — | — | EP | claimed |
| EP-1103248-A1 | Hair dyeing composition comprising N-ethyl-N-isopropyl-p-phenylenediamine | GOLDWELL GmbH (DE) | 2001-05-30 | — | — | EP | claimed |
| EP-0865465-B1 | LACCASES WITH IMPROVED DYEING PROPERTIES | NOVOZYMES AS (DK) | 2001-05-30 | — | — | EP | claimed |
| US-6001134-A | PERMANENT HAIR DYE | NOVO NORDISK A/S (DK) | 1999-12-14 | — | — | US | claimed |
| US-5948121-A | PERMANENT DYEING OF KERATINOUS FIBERS. LACCASE DERIVED FROM A STRAIN OF THE GENUS MYCELIOPHTHORA | NOVO NORDISK A/S (DK) | 1999-09-07 | — | — | US | claimed |
| EP-0891182-A1 | AN ENZYME FOR DYEING KERATINOUS FIBRES | NOVO NORDISK A/S (DK) | 1999-01-20 | — | — | EP | claimed |
| WO-1997037633-A1 | AN ENZYME FOR DYEING KERATINOUS FIBRES | NOVO NORDISK A/S (DK) | 1997-10-16 | — | — | WO | claimed |
| US-4149848-A | N-/TETRAHYDROFURFURYL/P-PHENYLENEDIAMINES | L'OREAL (FR) | 1979-04-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12564545-B2 | Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents | PHOSPHO1, ALDH7A1, AASDHPPT | TRPA1 306/4885PTGS1 1813/4885CACNA1C 2880/4885 |
| US-12636241-B1 | Method and composition for oxidative hair coloring | POLB, DAO, ALPP | TRPA1 1942/4885PTGS1 1483/4885CACNA1C 3338/4885 |
| US-20260144724-A1 | Mixture of at least five surfactants (I1) to (I5) | DEGS1, SGMS1, FABP4 | TRPA1 1372/4885PTGS1 2510/4885CACNA1C 3669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.