Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515128 | 0.98 | TSHR (0.50) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL9515062 | 0.93 | ALDH1A1 (0.47) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL987073 | 0.87 | NAAA (0.57) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL9513524 | 0.85 | HCAR2 (0.35) | TSHRFAAHZDHHC7HCAR2ALDH1A1 | |
| SCHEMBL4248770 | 0.79 | NAAA (0.57) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL9513561 | 0.79 | TSHR (0.53) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL9955198 | 0.78 | TSHR (0.72) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL2454309 | 0.78 | TSHR (0.72) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL2456606 | 0.78 | TSHR (0.72) | TSHRNAAARAD52NPSR1EPHX1 | |
| SCHEMBL9955486 | 0.78 | TSHR (0.72) | TSHRNAAARAD52NPSR1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274379-B1 | PROCESS FOR PREPARING PYRIDINE-2,3-DICARBOXYLIC ACID COMPOUNDS | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-4973695-A | FROM UNSATURATED ALDEHYDE OR KETONE WITH OXODIESTER | SUGAI CHEMICAL IND. CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| EP-0274379-A2 | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-07-13 | — | — | EP | disclosed |