Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780415 | 0.79 | FAAH (0.37) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL9780348 | 0.77 | LTA4H (0.38) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL14058643 | 0.74 | TSHR (0.38) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL28613980 | 0.73 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL8144722 | 0.72 | SMN1; SMN2 (0.39) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL9780419 | 0.69 | KMT2A (0.34) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL23929831 | 0.67 | LTA4H (0.37) | KMT2AMEN1LMNAGAAHTT | |
| SCHEMBL3836194 | 0.66 | MMP8 (0.58) | KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL8907300 | 0.64 | MEN1 (0.60) | KMT2AMEN1ALDH1A1GAAPOLB | |
| SCHEMBL4138448 | 0.64 | POLQ (0.36) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026717-A | Glutamate inhibitors | RHONE-POULENC SANTE (FR) | 1991-06-25 | — | — | US | disclosed |