SCHEMBL9860003

SCHEMBL9860003

CCO[Si](C)(CCc1ccccc1Sc1ccccc1CC[Si](C)(OCC)OCC)OCC

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 8/20 0.35
SLC6A2 P23975 7/20 0.35
SLC6A3 Q01959 6/20 0.35
LMNA P02545 2/20 0.35
P4HB P07237 1/20 0.34
KMT2A Q03164 2/20 0.33
IFNAR1 P17181 1/20 0.33
ALDH1A1 P00352 1/20 0.33
NPY1R P25929 1/20 0.33
MAPK1 P28482 1/20 0.33
NPY2R P49146 1/20 0.33
CHRNA7 P36544 1/20 0.32
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9860017 0.87
SCHEMBL3337265 0.78 CYP4F2 (0.32) ALDH1A1
SCHEMBL1637617 0.75 CYP4F2 (0.38) MAPTL3MBTL1
SCHEMBL8347602 0.73 TP53 (0.31) POLB
SCHEMBL2872464 0.73 TDP1 (0.41) SLC6A4SLC6A2SLC6A3ALDH1A1MAPT
SCHEMBL577212 0.72 SLC6A4 (0.44) SLC6A4SLC6A2SLC6A3LMNAP4HB
SCHEMBL16062863 0.70 CYP4F2 (0.36) KMT2A
SCHEMBL9860010 0.69 SLC6A4 (0.32) SLC6A4LMNA
SCHEMBL7921225 0.69 APOBEC3G (0.39) KMT2AMEN1MAPT
SCHEMBL1576764 0.69 LIPG (0.46) SLC6A4SLC6A2SLC6A3LMNAIFNAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5015717-A Sulfur-containing organopolysiloxane waxes and a method for preparing the same WACKER SILICONES CORPORATION (US) 1991-05-14 US disclosed
EP-0274100-A2 Sulfur containing organopolysiloxane waxes and a method for preparing the same Wacker Silicones Corporation (US) 1988-07-13 EP disclosed