Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9113426 | 0.78 | LMNA (0.52) | LMNAPOLB | |
| SCHEMBL9873666 | 0.78 | LMNA (0.52) | LMNAPOLB | |
| SCHEMBL9873178 | 0.78 | LMNA (0.52) | LMNAPOLB | |
| SCHEMBL9873057 | 0.78 | LMNA (0.52) | LMNAPOLB | |
| SCHEMBL9114789 | 0.78 | LMNA (0.52) | LMNAPOLB | |
| SCHEMBL9873430 | 0.78 | LMNA (0.52) | LMNAPOLB | |
| SCHEMBL9872933 | 0.78 | LMNA (0.52) | LMNAPOLB | |
| SCHEMBL9873695 | 0.76 | MEN1 (0.48) | LMNAPOLBRAB9ANPC1KMT2A | |
| SCHEMBL9873092 | 0.73 | LMNA (0.56) | LMNAPOLBRAB9ANPC1KMT2A | |
| SCHEMBL9135952 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017150-A1 | TETRAZOLE UREA AND THIOUREA ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-11-14 | — | — | WO | disclosed |