SCHEMBL10000387

SCHEMBL10000387

C=CC(=O)OC1CCC(C2CCC(C)CC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.36
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465372 0.94 CYP19A1 (0.39) CYP19A1NPC1ALDH1A1LMNAMAPT
SCHEMBL9979753 0.90 TSHR (0.32) ALDH1A1
SCHEMBL23494072 0.87 CYP19A1 (0.36) CYP19A1NPC1ALDH1A1LMNAMAPT
SCHEMBL19884704 0.85 EPHX2 (0.30)
SCHEMBL17677318 0.85 CHRM2 (0.33) ALDH1A1
SCHEMBL321481 0.84 TSHR (0.36) ALDH1A1LMNASMN1; SMN2
SCHEMBL34965 0.84
SCHEMBL2530486 0.83 CYP19A1 (0.42) CYP19A1
SCHEMBL13283558 0.83
SCHEMBL10233841 0.83 EPHX1 (0.36) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8094263-B2 Optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-10 US disclosed
US-8007877-B2 Liquid crystal optical modulation element and optical head device ASAHI GLASS COMPANY, LIMITED (JP) 2011-08-30 US disclosed
US-20110037910-A1 LIQUID CRYSTAL OPTICAL MODULATION ELEMENT AND OPTICAL HEAD DEVICE ASAHI GLASS COMPANY, LIMITED (JP) 2011-02-17 US disclosed
US-7820250-B2 Liquid crystal optical modulation element and optical head device ASAHI GLASS COMPANY, LIMITED (JP) 2010-10-26 US disclosed
US-20100053509-A1 OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed
US-20070102669-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND OPTICAL ANISOTROPIC MATERIAL ASAHI GLASS COMPANY, LIMITED (JP) 2007-05-10 US disclosed
US-20070104894-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIC MATERIAL AND OPTICAL ELEMENT ASAHI GLASS CO., LTD. (JP) 2007-05-10 US disclosed