Targets

A few well-known targets below — or search any of 4,884 human protein targets in the bar above. Each links to the patented chemistry predicted against it.

EGFR

Epidermal growth factor receptor (EC 2.7.10.1

1,251,638 predicted compounds

BRAF

Serine/threonine-protein kinase B-raf (EC 2.7

386,360 predicted compounds

ABL1

Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (A

741,027 predicted compounds

ALK

ALK tyrosine kinase receptor (EC 2.7.10.1) (A

402,917 predicted compounds

BTK

Tyrosine-protein kinase BTK (EC 2.7.10.2) (Ag

560,113 predicted compounds

JAK2

Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (J

941,107 predicted compounds

KDR

Vascular endothelial growth factor receptor 2

1,160,784 predicted compounds

CDK6

Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cel

146,778 predicted compounds

ERBB2

Receptor tyrosine-protein kinase erbB-2 (EC 2

385,121 predicted compounds

KRAS

GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (

256,974 predicted compounds

PARP1

Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2

564,538 predicted compounds

PTGS2

Prostaglandin G/H synthase 2 (EC 1.14.99.1) (

1,154,075 predicted compounds

ACE

Angiotensin-converting enzyme (ACE) (EC 3.4.1

214,494 predicted compounds

HMGCR

3-hydroxy-3-methylglutaryl-coenzyme A reducta

72,679 predicted compounds

DPP4

Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP)

530,164 predicted compounds

PDE5A

cGMP-specific 3',5'-cyclic phosphodiesterase

246,286 predicted compounds

ESR1

Estrogen receptor (ER) (ER-alpha) (Estradiol

1,142,324 predicted compounds

DRD2

D(2) dopamine receptor (Dopamine D2 receptor)

1,185,435 predicted compounds

ADRB2

Beta-2 adrenergic receptor (Beta-2 adrenorece

444,598 predicted compounds

HTR2A

5-hydroxytryptamine receptor 2A (5-HT-2) (5-H

1,336,899 predicted compounds