Targets
A few well-known targets below — or search any of 4,884 human protein targets in the bar above. Each links to the patented chemistry predicted against it.
EGFR
Epidermal growth factor receptor (EC 2.7.10.1
1,251,638 predicted compounds
BRAF
Serine/threonine-protein kinase B-raf (EC 2.7
386,360 predicted compounds
ABL1
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (A
741,027 predicted compounds
ALK
ALK tyrosine kinase receptor (EC 2.7.10.1) (A
402,917 predicted compounds
BTK
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Ag
560,113 predicted compounds
JAK2
Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (J
941,107 predicted compounds
KDR
Vascular endothelial growth factor receptor 2
1,160,784 predicted compounds
CDK6
Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cel
146,778 predicted compounds
ERBB2
Receptor tyrosine-protein kinase erbB-2 (EC 2
385,121 predicted compounds
KRAS
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (
256,974 predicted compounds
PARP1
Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2
564,538 predicted compounds
PTGS2
Prostaglandin G/H synthase 2 (EC 1.14.99.1) (
1,154,075 predicted compounds
ACE
Angiotensin-converting enzyme (ACE) (EC 3.4.1
214,494 predicted compounds
HMGCR
3-hydroxy-3-methylglutaryl-coenzyme A reducta
72,679 predicted compounds
DPP4
Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP)
530,164 predicted compounds
PDE5A
cGMP-specific 3',5'-cyclic phosphodiesterase
246,286 predicted compounds
ESR1
Estrogen receptor (ER) (ER-alpha) (Estradiol
1,142,324 predicted compounds
DRD2
D(2) dopamine receptor (Dopamine D2 receptor)
1,185,435 predicted compounds
ADRB2
Beta-2 adrenergic receptor (Beta-2 adrenorece
444,598 predicted compounds
HTR2A
5-hydroxytryptamine receptor 2A (5-HT-2) (5-H
1,336,899 predicted compounds