SCHEMBL10000442

SCHEMBL10000442

Cc1ccc(Oc2cccc(Oc3ccc(N4C(=O)c5ccc(Oc6ccc(C)cc6)cc5C4=O)cc3)c2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.74
MEN1 O00255 6/20 0.67
KMT2A Q03164 6/20 0.67
ALDH1A1 P00352 6/20 0.57
GAA P10253 1/20 0.57
RAB9A P51151 2/20 0.55
NPC1 O15118 1/20 0.55
TSHR P16473 1/20 0.55
CASP1 P29466 1/20 0.55
CASP7 P55210 1/20 0.55
HSD17B10 Q99714 1/20 0.55
HTT P42858 2/20 0.54
NPSR1 Q6W5P4 3/20 0.54
MAPT P10636 3/20 0.54
TDP1 Q9NUW8 1/20 0.54
LPAR1 Q92633 2/20 0.53
LPAR3 Q9UBY5 2/20 0.53
POLB P06746 1/20 0.52
MAPK1 P28482 1/20 0.52
PKM P14618 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13899501 0.94 MEN1 (0.70) BRD4MEN1KMT2AALDH1A1GAA
SCHEMBL10000451 0.91 BRD4 (0.63) BRD4MEN1KMT2AALDH1A1GAA
SCHEMBL13678848 0.90 MEN1 (0.69) BRD4MEN1KMT2AALDH1A1GAA
SCHEMBL92527 0.88 BRD4 (0.60) BRD4MEN1KMT2AALDH1A1GAA
SCHEMBL12317361 0.88 BRD4 (0.60) BRD4MEN1KMT2AALDH1A1GAA
SCHEMBL14010059 0.88 BRD4 (0.60) BRD4MEN1KMT2AALDH1A1GAA
SCHEMBL760105 0.88 MEN1 (0.64) BRD4MEN1KMT2AALDH1A1GAA
SCHEMBL12792336 0.88 CA9 (0.63) BRD4MEN1KMT2AALDH1A1GAA
SCHEMBL13923538 0.88 CA9 (0.63) BRD4MEN1KMT2AALDH1A1GAA
SCHEMBL17272758 0.88 BRD4 (0.73) BRD4MEN1KMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8289833-B2 Method for high density data storage and imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-10-16 US disclosed
US-20120033539-A1 METHOD FOR HIGH DENSITY DATA STORAGE AND IMAGING INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-02-09 US disclosed