⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16556494 | 0.80 | TRPV1 (0.31) | — | |
| SCHEMBL12154461 | 0.78 | — | — | |
| SCHEMBL24041230 | 0.77 | — | — | |
| SCHEMBL13970891 | 0.72 | — | — | |
| SCHEMBL14574324 | 0.72 | — | — | |
| SCHEMBL12514536 | 0.72 | — | — | |
| SCHEMBL12020188 | 0.71 | — | — | |
| SCHEMBL22563328 | 0.71 | — | — | |
| SCHEMBL6262189 | 0.71 | — | — | |
| SCHEMBL14308877 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2893343-B1 | METHODS FOR DIAGNOSIS OF INFLAMMATORY LIVER DISEASE | UNIV ALBERTA (CA) | 2019-11-20 | — | — | EP | disclosed |
| US-20130035367-A1 | ANTISENSE OLIGONUCLEOTIDES THAT TARGET A CRYPTIC SPLICE SITE IN USH1C AS A THERAPEUTIC FOR USHER SYNDROME | ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE (US) | 2013-02-07 | — | — | US | disclosed |
| US-20120165389-A1 | ANTISENSE OLIGONUCLEOTIDES THAT TARGET A CRYPTIC SPLICE SITE IN USH1C AS A THERAPEUTIC FOR USHER SYNDROME | ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE | 2012-06-28 | — | — | US | disclosed |
| US-7211432-B2 | Recombinant vector expressing multiple costimulatory molecules and uses thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2007-05-01 | — | — | US | disclosed |