SCHEMBL10000520

SCHEMBL10000520

Cc1ccc(N2C(=O)c3ccc(Oc4ccc(C(C)(C)c5ccc(Oc6ccc7c(c6)C(=O)N(c6cccc(N8C(=O)c9ccc(C#Cc%10ccccc%10)cc9C8=O)c6)C7=O)cc5)cc4)cc3C2=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.52
KMT2A Q03164 6/20 0.52
BRD4 O60885 1/20 0.45
ALDH1A1 P00352 4/20 0.44
MAPT P10636 2/20 0.44
POLB P06746 2/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.43
PKM P14618 1/20 0.42
MCHR1 Q99705 1/20 0.41
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
LPAR1 Q92633 2/20 0.40
LPAR3 Q9UBY5 2/20 0.40
LPAR5 Q9H1C0 1/20 0.39
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA9 Q16790 2/20 0.38
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14259658 0.98 MEN1 (0.50) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL14114060 0.94 MEN1 (0.48) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL14678624 0.92 MEN1 (0.46) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL10000526 0.92 BRD4 (0.47) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL10000441 0.91 KMT2A (0.49) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL22566814 0.91 KMT2A (0.46) MEN1KMT2ABRD4POLBHTT
SCHEMBL10000439 0.89 MEN1 (0.47) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL10000527 0.89 MEN1 (0.46) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL13678849 0.88 MEN1 (0.61) MEN1KMT2ABRD4ALDH1A1MAPT
SCHEMBL84247 0.87 MEN1 (0.58) MEN1KMT2ABRD4ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8369204-B2 Method for high density data storage and imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-02-05 US disclosed
US-20120034383-A1 METHOD FOR HIGH DENSITY DATA STORAGE AND IMAGING INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-02-09 US disclosed
US-8102753-B2 Method for forming deformed regions in a resin layer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-01-24 US disclosed
US-20070196645-A1 Method for high density data storage and imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-08-23 US disclosed