Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16349362 | 0.99 | MAPT (0.40) | MAPTALDH1A1LMNAGAACYP2C9 | |
| SCHEMBL29989 | 0.85 | ACACB (0.38) | MAPTALDH1A1LMNACYP2C9ACACB | |
| SCHEMBL9160404 | 0.83 | MEN1 (0.40) | MAPTALDH1A1LMNAGAACYP2C9 | |
| SCHEMBL9160407 | 0.83 | MEN1 (0.40) | MAPTALDH1A1LMNAGAACYP2C9 | |
| SCHEMBL11069053 | 0.82 | MAPT (0.40) | MAPTALDH1A1LMNAGAACYP2C9 | |
| SCHEMBL11070673 | 0.82 | MAPT (0.40) | MAPTALDH1A1LMNAGAACYP2C9 | |
| SCHEMBL30001 | 0.82 | MAPT (0.40) | MAPTALDH1A1LMNAGAACYP2C9 | |
| SCHEMBL11070687 | 0.82 | MAPT (0.40) | MAPTALDH1A1LMNAGAACYP2C9 | |
| SCHEMBL2860558 | 0.81 | KDM4E (0.39) | ALDH1A1KMT2ASMN1; SMN2ACACB | |
| SCHEMBL9798006 | 0.80 | KDM4E (0.53) | MAPTALDH1A1GAACYP2C9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| EP-2609172-B1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |
| EP-2423294-A1 | Switch element comprising a liquid-crystalline medium | Merck Patent GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |