Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 10/20 | 0.44 |
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | MECP2 | P51608 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13230232 | 0.92 | S1PR1 (0.49) | S1PR1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL10820026 | 0.92 | NPC1 (0.47) | S1PR1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL13230234 | 0.92 | S1PR1 (0.49) | S1PR1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL10820025 | 0.91 | S1PR1 (0.48) | S1PR1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL12680716 | 0.91 | S1PR1 (0.45) | S1PR1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL10001253 | 0.90 | S1PR1 (0.45) | S1PR1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL12680744 | 0.89 | S1PR1 (0.47) | S1PR1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL13230198 | 0.88 | S1PR1 (0.46) | S1PR1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL13230183 | 0.88 | S1PR1 (0.46) | S1PR1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL614797 | 0.87 | NPC1 (0.51) | S1PR1NPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859113-B2 | Carbazole derivatives and organic light-emitting diode device using the same | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2014-10-14 | — | — | US | disclosed |
| US-8859113-B2 | Carbazole derivatives and organic light-emitting diode device using the same | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2014-10-14 | — | — | US | disclosed |
| US-20140175400-A1 | Novel Carbazole Derivatives and Organic Light-Emitting Diode Device Using the Same | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2014-06-26 | — | — | US | disclosed |
| US-20140175400-A1 | Novel Carbazole Derivatives and Organic Light-Emitting Diode Device Using the Same | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2014-06-26 | — | — | US | disclosed |
| US-8580396-B2 | Carbazole derivatives and organic light-emitting diode device using the same | China Petrochemical Development Corp (TW) | 2013-11-12 | — | — | US | disclosed |
| US-8580396-B2 | Carbazole derivatives and organic light-emitting diode device using the same | China Petrochemical Development Corp (TW) | 2013-11-12 | — | — | US | disclosed |
| US-20120038264-A1 | Novel Carbazole Derivatives and Organic Light-Emitting Diode Device Using the Same | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2012-02-16 | — | — | US | disclosed |
| US-20120038264-A1 | Novel Carbazole Derivatives and Organic Light-Emitting Diode Device Using the Same | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120038264-A1 | Novel Carbazole Derivatives and Organic Light-Emitting Diode Device Using the Same | DRD1, DRD3, CYBA | S1PR1 4757/4885NPC1 510/4885RAB9A 2658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.