Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13989307 | 0.88 | HTT (0.50) | KDM4EALOX15HSD17B10ADRB2ADRB1 | |
| SCHEMBL10001673 | 0.88 | KDM4E (0.44) | KDM4EALOX15HSD17B10ADRB2ADRB1 | |
| SCHEMBL25602364 | 0.85 | USP2 (0.53) | KDM4EALOX15HSD17B10USP2CA12 | |
| SCHEMBL13678875 | 0.85 | USP2 (0.53) | KDM4EALOX15HSD17B10USP2CA12 | |
| SCHEMBL24840347 | 0.84 | KDM4E (0.48) | KDM4EALOX15HSD17B10ADRB2ADRB1 | |
| SCHEMBL27322291 | 0.83 | USP2 (0.61) | KDM4EALOX15HSD17B10USP2HTT | |
| SCHEMBL13882631 | 0.83 | — | — | |
| SCHEMBL16089122 | 0.82 | — | — | |
| SCHEMBL2891621 | 0.82 | — | — | |
| SCHEMBL2891619 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8505743-B2 | Surface modification of polyamide reverse osmosis membranes | MICHIGAN MOLECULAR INSTITUTE (US) | 2013-08-13 | — | — | US | disclosed |
| US-20120024789-A1 | Surface Modification of Polyamide Reverse Osmosis Membranes | MICHIGAN MOLECULAR INSTITUTE (US) | 2012-02-02 | — | — | US | disclosed |