Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10001677 | 0.89 | HSD17B10 (0.46) | HTTUSP2HSD17B10HIF1ALMNA | |
| SCHEMBL10001679 | 0.83 | HIF1A (0.44) | HTTUSP2HSD17B10HIF1ALMNA | |
| SCHEMBL14507015 | 0.83 | HSD17B10 (0.56) | HTTUSP2HSD17B10HIF1ALMNA | |
| SCHEMBL7296353 | 0.81 | USP2 (0.55) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL5021533 | 0.80 | MEN1 (0.61) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL18251584 | 0.80 | MEN1 (0.61) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL3542017 | 0.80 | MEN1 (0.61) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL347384 | 0.80 | HIF1A (0.47) | HTTUSP2HSD17B10HIF1ALMNA | |
| SCHEMBL10001678 | 0.80 | HSD17B10 (0.39) | HTTUSP2HSD17B10HIF1ALMNA | |
| SCHEMBL10884401 | 0.79 | HSD17B10 (0.41) | HTTUSP2HSD17B10HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8505743-B2 | Surface modification of polyamide reverse osmosis membranes | MICHIGAN MOLECULAR INSTITUTE (US) | 2013-08-13 | — | — | US | disclosed |
| US-20120024789-A1 | Surface Modification of Polyamide Reverse Osmosis Membranes | MICHIGAN MOLECULAR INSTITUTE (US) | 2012-02-02 | — | — | US | disclosed |