SCHEMBL10001732

SCHEMBL10001732

CC1CCC(C2CCC(c3ccc(OC(F)(F)F)c(F)c3)CC2)CC1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.38
PDE2A O00408 7/20 0.38
EPHX2 P34913 5/20 0.38
KDM1A O60341 3/20 0.35
FFAR4 Q5NUL3 1/20 0.34
HCRTR1 O43613 2/20 0.34
HCRTR2 O43614 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14281232 0.89 PDE2A (0.39) ESR2PDE2AEPHX2KDM1AHCRTR1
SCHEMBL8768349 0.89 EPHX2 (0.39) PDE2AEPHX2KDM1AFFAR4HCRTR1
SCHEMBL16325994 0.89 TRPV1 (0.33) ESR2PDE2AEPHX2KDM1A
SCHEMBL12997536 0.88 EPHX2 (0.45) PDE2AEPHX2KDM1A
SCHEMBL17179140 0.87 PDE2A (0.35) PDE2AEPHX2
SCHEMBL20967289 0.87 S1PR1 (0.39) PDE2AEPHX2KDM1AFFAR4HCRTR1
SCHEMBL13345610 0.86 EPHX2 (0.38) PDE2AEPHX2KDM1AFFAR4
SCHEMBL10014267 0.86 FASN (0.39) ESR2PDE2AEPHX2
SCHEMBL14268565 0.85 PDE2A (0.39) PDE2AEPHX2KDM1AHCRTR1HCRTR2
SCHEMBL10014234 0.85 GRIN2B (0.38) ESR2EPHX2HCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
WO-2024017812-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-01-25 WO disclosed
EP-4279565-A2 THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME Merck Patent GmbH (DE) 2023-11-22 EP disclosed
EP-3980510-B1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2023-11-08 EP disclosed
EP-3679111-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2023-11-01 EP disclosed
US-11795398-B2 Liquid-crystalline medium and liquid-crystal display comprising the same and compounds MERCK PATENT GMBH (DE) 2023-10-24 US disclosed
US-11795398-B2 Liquid-crystalline medium and liquid-crystal display comprising the same and compounds MERCK PATENT GMBH (DE) 2023-10-24 US disclosed
EP-4261267-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2023-10-18 EP disclosed
US-11788009-B2 Liquid-crystalline medium for use in a switching element MERCK PATENT GMBH (DE) 2023-10-17 US disclosed
US-20070237907-A1 PHOTOSTABLE LIQUID-CRYSTALLINE MEDIUM MANABE ATSUTAKA 2007-10-11 US disclosed
US-7270856-B2 Cyclobutane derivatives MERCK PATENT GMBH (DE) 2007-09-18 US disclosed
EP-1832643-A1 Liquid crystalline medium and liquid-crystal display Merck Patent GmbH (DE) 2007-09-12 EP disclosed
US-7250198-B2 For electrooptical display MERCK PATENT GMBH (DE) 2007-07-31 US disclosed
US-20070104895-A1 LIQUID CRYSTAL OPTICAL MODULATION ELEMENT AND OPTICAL HEAD DEVICE ASAHI GLASS COMPANY, LIMITED (JP) 2007-05-10 US disclosed
US-7211302-B2 Photostable liquid crystalline medium MERCK PATENT GMBH (DE) 2007-05-01 US disclosed
US-7189440-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2007-03-13 US disclosed
US-7179511-B2 For use in electro-optical displays MERCK PATENT GMBH (DE) 2007-02-20 US disclosed
US-20070034828-A1 Containing 3 directly connected rings: a fluorophenyl ring, a tetrahydropyran ring and either another tetrahydropyran ring or a 1,3-dioxane ring; electrooptical displays; MERCK PATENT GMBH (DE) 2007-02-15 US disclosed
US-20070001149-A1 Liquid-crystal medium containing monofluoroterphenyl compounds MERCK PATENT GMBH (DE) 2007-01-04 US disclosed