SCHEMBL10002084

SCHEMBL10002084

CC(O)(c1ccc2cc3c(N)c(C(O)(C(F)(F)F)C(F)(F)F)ccc3cc2c1N)C(F)(F)F

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.58
▸ MEN1 O00255 2/20 0.58
▸ MAPT P10636 2/20 0.58
▸ KMT2A Q03164 2/20 0.58
▸ ALDH1A1 P00352 1/20 0.58
▸ GLA P06280 1/20 0.58
▸ POLB P06746 1/20 0.58
▸ GAA P10253 1/20 0.58
▸ HPGD P15428 1/20 0.58
▸ ATM Q13315 1/20 0.58
▸ HSD17B10 Q99714 1/20 0.58
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ LMNA P02545 1/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ HTT P42858 1/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.47
▸ KCNJ11 Q14654 16/20 0.45
▸ ABCC9 O60706 8/20 0.40
▸ ABCC8 Q09428 8/20 0.40
▸ KCNJ8 Q15842 8/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10036538 0.90 KDM4E (0.69) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL2784084 0.87 KDM4E (0.65) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL2783508 0.87 KDM4E (0.65) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL2784574 0.87 KDM4E (0.65) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL10002082 0.87 KDM4E (0.56) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL2784493 0.87 KDM4E (0.65) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL2782869 0.85 KDM4E (0.67) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL12126496 0.84 KDM4E (0.53) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL12126507 0.84 MEN1 (0.57) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL2784774 0.81 KDM4E (0.58) KDM4EMEN1MAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170144113-A1 COMPOSITE MEMBRANE WITH MULTI-LAYERED ACTIVE LAYER INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-05-25 — — US disclosed
US-9561474-B2 Composite membrane with multi-layered active layer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-02-07 — — US disclosed
US-20170001151-A1 ANTIFOULING AND ANTIMICROBIAL COATINGS FOR THIN FILM COMPOSITE MEMBRANES INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-01-05 — — US disclosed
US-9504967-B2 Composite membrane with multi-layered active layer GLOBALFOUNDRIES INC. (KY) 2016-11-29 — — US disclosed
US-20140353253-A1 COMPOSITE MEMBRANE WITH MULTI-LAYERED ACTIVE LAYER GLOBALFOUNDRIES U.S. INC. 2014-12-04 — — US disclosed
US-8857629-B2 Composite membrane with multi-layered active layer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-10-14 — — US disclosed
US-8809451-B2 Fluorinated dicarboxylic acid derivative and polymer obtained therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2014-08-19 — — US disclosed
US-20130085237-A1 Fluorinated Diamine and Polymer Formed Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2013-04-04 — — US disclosed
US-8304508-B2 Fluorine-containing dicarboxylic acids and their novel polymer compounds CENTRAL GLASS COMPANY, LIMITED (JP) 2012-11-06 — — US disclosed
US-20120012527-A1 COMPOSITE MEMBRANE WITH MULTI-LAYERED ACTIVE LAYER INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-01-19 — — US disclosed
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-08 — — US disclosed
US-20110282026-A1 Fluorine-Containing Dicarboxylic Acids and Their Novel Polymer Compounds CENTRAL GLASS COMPANY, LIMITED (JP) 2011-11-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom MCCC2, AFF2, F13A1 KDM4E 2650/4885MEN1 1359/4885MAPT 3852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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