Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of 4,4-Difluoro-Piperidinium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4,4-Difluoro-Piperidinium SCHEMBL13457 | 0.96 | — | — | |
| 4,4-Difluoro-Piperidinium SCHEMBL29154751 | 0.93 | — | — | |
| 4,4-Difluoro-Piperidinium SCHEMBL16582 | 0.93 | — | — | |
| 4,4-Difluoro-Piperidinium SCHEMBL19410291 | 0.93 | — | — | |
| 4,4-Difluoro-Piperidinium SCHEMBL27142480 | 0.93 | HIF1A (0.33) | — | |
| 4,4-Difluoro-Piperidinium SCHEMBL22288728 | 0.90 | — | — | |
| SCHEMBL2519854 | 0.84 | — | — | |
| 4,4-Difluoro-Piperidinium SCHEMBL28740341 | 0.84 | — | — | |
| SCHEMBL21039320 | 0.82 | CXCR4 (0.42) | — | |
| Hydrochloric Acid SCHEMBL937458 | 0.82 | CXCR4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115386363-B | One-dimensional organic-inorganic hybrid double perovskite fluorescent material and preparation method thereof | 山东大学 | 2024-03-12 | — | — | CN | disclosed |
| CN-115386363-A | One-dimensional organic-inorganic hybrid double perovskite fluorescent material and preparation method thereof | 山东大学 | 2022-11-25 | — | — | CN | disclosed |
| EP-2280001-B1 | LONG-CHAIN FATTY ACID ELONGATION ENZYME INHIBITOR COMPRISING ARYLSULFONYL DERIVATIVE AS ACTIVE INGREDIENT | MSD KK (JP) | 2014-10-15 | — | — | EP | disclosed |
| US-8420823-B2 | Long-chain fatty acyl elongase inhibitor comprising arylsulfonyl derivative as active ingredient | MSD K.K. (JP) | 2013-04-16 | — | — | US | disclosed |
| EP-2280001-A1 | LONG-CHAIN FATTY ACID ELONGATION ENZYME INHIBITOR COMPRISING ARYLSULFONYL DERIVATIVE AS ACTIVE INGREDIENT | Banyu Pharmaceutical Co., Ltd. (JP) | 2011-02-02 | — | — | EP | disclosed |
| US-20110009622-A1 | LONG-CHAIN FATTY ACYL ELONGASE INHIBITOR COMPRISING ARYLSULFONYL DERIVATIVE AS ACTIVE INGREDIENT | MSD K.K. (JP) | 2011-01-13 | — | — | US | disclosed |