Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10432573 | 1.00 | HTR2A (0.33) | HTR2AHTR2CHTR2BGRIA4KDM1A | |
| SCHEMBL12917849 | 0.86 | ESR2 (0.34) | ESR2 | |
| SCHEMBL2741533 | 0.84 | — | — | |
| SCHEMBL10432495 | 0.84 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL10432496 | 0.84 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL10432494 | 0.84 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL9785330 | 0.84 | HTR2A (0.38) | HTR2AHTR2CHTR2BGRIA4KDM1A | |
| SCHEMBL18176037 | 0.84 | HTR2A (0.38) | HTR2AHTR2CHTR2BGRIA4KDM1A | |
| SCHEMBL10502319 | 0.84 | CYP11B1 (0.45) | KDM1A | |
| SCHEMBL9556571 | 0.84 | CYP11B1 (0.45) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400861-A1 | 1,3-dioxane derivative and liquid crystal composition incorporating the same | SEIKO EPSON CORPORATION (JP) | 1990-12-05 | — | — | EP | claimed |
| US-9238775-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2016-01-19 | — | — | US | disclosed |
| US-20130208227-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| WO-2012052100-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |
| EP-0400861-A1 | 1,3-dioxane derivative and liquid crystal composition incorporating the same | SEIKO EPSON CORPORATION (JP) | 1990-12-05 | — | — | EP | disclosed |